Dexamethasone pre- Docetaxel regimen?

  • 5 replies
  • 281 subscribers
  • 656 views

Hi guys,  I am starting Docetaxel (Taxotere) at 2pm tomorrow. I have been given steroids to start 24hrs before - I took that literally and took a dose at 2pm.  It then says morning and night on the bottle.

i am slightly confused if I should be taking another tonight. Or 2 lots more before chemo tomorrow. I just wondered how everyone else did it? From searching the forum I can see a lot of people did 2 full doses the day before chemo. Doing one as early as possible and another 6 hours later so they weren’t taking too late in the day. So perhaps they did another 1 or even 2 before their actual chemo on the day. What did you do? Are people taking 2,3 or 4 doses before they do Docetaxel? 

I am waiting for a call back from the out of hours chemo team to ask them. But I guess you wonderful people will know best what worked for you…. I’d rather not be taking steroids at 9pm! But I also don’t want to risk a bad reaction by not taking enough in advance. Conversely, I don’t want to take too many before the chemo then perhaps only have 2 doses for after which maybe isn’t enough? 

Any advice is greatly appreciated! 

  • Hi, I didn’t want to let you post go unread for long as I can imagine you might be sitting at home worrying.  I think I took the steroid morning and lunchtime the day before, day of and day after chemo. I am pretty sure the reason for this is they tend to keep you awake, so best not to take too late in the day, but it's 18 months ago now and my fuzzy brain can't quite remember. I hope by now you've had your call back. Best wishes 

    Community Champion badge

  • Hi I agree morning and lunchtime so as to not keep you awake.x

  • Hi, thank you so much for answering. I think you’re right & in future that’s the way I’ll do it. 

    I did not have much luck with the out of hours service- I was told to call the chemo unit tomorrow, which would be too late. 

    Reading up on various medical facilities protocols it seems the consensus is that 3 doses beforehand is optimum. I’ve only taken 1 today, but figure I’ll wake up super early and get 2 in before I start chemo at 2pm and hopefully that’s alright. Thanks for your help. 

  • Thanks for the reply. I will definitely do that next time. I have messed up today a bit by taking the 24hrs before so literally. But it seems the answer is 3 doses before chemo and I can still do that if I wake up early. So I think it’s all good! 

  • Am sure you'll be fine, And good luck for today's chemo.

    Community Champion badge