ER positive Her Negative metastatic breast cancer in bones

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  • Primary breast cancer in 2016. Lumpectomy, radiation and Letrozole. July 2025 lesions found on MRI for something else. Confirmed MBC in October 25. Retired 73 years old. About to start Denumosab and Radio to sacrum plus Letrozole Sacral lesion causing bladder and bowel irritation. Anyone else experienced this? 
  • Hi Timotea.  I am sorry to hear you have secondary cancer.  I had cancer in 2013, with chemo, radiotherapy and tamoxifen.  Last year had hip and back pain was diagnosed in September 24 with secondary breast cancer with mets in pelvis, hips, spine, ribs and skull.  Lately I am having pain in the sacrum area too and have bladder issues.  I only have an appointment with oncologist on 19 November so will ask about this pain.  I think I probably have mets there too.  I had radiotherapy a few months ago to my spine for pain and it helped.  I am on exemastane, ribociclib and denosumab injections.  I have just turned 60.  Big hugs.

    Lee x