Since my operation and hormone medication and five sessions of radiotherapy I have become very fatigued to the point where it’s becoming difficult to do everyday tasks., I also have severe joint and muscle pain. I realise these are the side affects but wonder if an alternative hormone treatment would be better. Thank you
Hi. You don't say how long you have been on Letrozole for. I also has 5 doses of radiotherapy a month after starting on Letrozole.
It took a couple of months before I started to feel less tired. Hopefully you will start to feel better. If not, have a word with your bcn or GP. The brand can also have an impact as individuals sometimes tolerate one brand better than another.
I hope you feel better soon xx
Hi I’m new here
took letrozole for 3 months had the same everyside effect there was fatigue was getting worse! Came off them over Christmas and started tamoxifen and my luck exactly the same side effects are as bad getting I can’t do my daily routine just want to lie there !! I’m a really positive person trying to do all the right things excerise ear health food any one else experiencing this or I’m just one of the unlucky ones thanks
Hi, I have heard about some people changing brands and finding that this has worked. Seems weird to me, but it does seem that different manufacturers mix something different with the actual medication and this can make a difference. Might be worth a discussion with your GP or pharmacy. Best wishes
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2025 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007