Struggling with S/E of Abemaciclib

Hi Dr Hoq

Welcome to the forum and sorry to hear that you are suffering from side effects from Abemaciclib.  While I don't have the experience you are looking for I noticed that you haven't had any answers yet so I thought I'd welcome you to the forum.  This reply will move you to the top of the discussion.  Hopefully someone will be along shortly with an answer for you.

Best wishes

Daisy53

Hi , I have had stomach cramps, but at moment feel sick I was on it three weeks then had to go on antibiotics due to fluid in the ear so was took off it now. back on it and got this sickness never had before huh . 

I think a lot struggle to get the dose right and control the initial symptoms. I think it often settles down a bit and you learn what works best for you. I hope the pain has settled down now x

Hi.  it makes sense to stop whatever caused the problem. I have three friends on one teaspoon of bicarb and one teaspoon of honey mixed in WARM water twice a day for ten days then maintenance every ten days of three days back on it . They all seem to be doing well. It alkalises the body as too acid is out of balance. 

Hi how are you getting on now with the tablets? 

Hi how are you getting on now with these tablets? 

Hi 

I’m due to start these next week and I’m pretty worried about the side effects . How are you feeling now ? 
xx

Hi

I was so sick since I start taking Abemaciclib. Oncologist reduced the dose but side effects still there. Today I read patients review regarding Abemaciclib in the MacMillan group. Its causes IBS type symptoms! Severe abdominal cramps, diarrhoea, fatigue. Its been 6 weeks I am suffering. I took 40 Loperamide capsules. I loose 8 kilos weight. I can't eat, can't sleep, totally bedridden. I was continuously asking my doctors to help me but they said it will take time to adjust with body. Nobody warned me about IBS, they can prescribe anti spasmodic for my abdominal pain, but unfortunately they didn't. Tomorrow I will call my gp and definitely I will ask him/ her why they didn't take a look to their books and treat me accordingly if they are not sure about it. Why why why!! Everyday I cried due to severe pain, my son was upset, he thought I'm gonna die soon! He prayed every night for me before sleeping. I am totally devastated. Please talk to oncologist if you suffer any kind of side effects. Its vary from patient to patient. Good luck.

Hi D Hog I had to give up taking these tablets I was in so much pain . Then my blood count dropped making me feel even worse and that was on a very reduced does 50 mg . Most people can take this drubut I was unlucky my body wanted tolerate it . Good luck with the treatment you are not alone xx 

Sorry I meant wouldn’t take it . X