Trials using the DON antibiotic in combo woth keto diet

FormerMember
FormerMember
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https://www.sciencedaily.com/releases/2019/05/190530154220.htm

Anyone know of any?

Its a May 2019 trial results featured

See also

https://www.hindawi.com/journals/bmri/2015/690492/

Regards

Kkeith

  • Hi , I don’t know if you’ve tried this cancer research link to see if you can find what your looking for.

    https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial

    Best wishes

    Take care KT

  • FormerMember
    FormerMember in reply to KTatHome

    Thanks KT. It doesnt look like there is anything happening.

    From what Ive read it looks like a potentially treatment so I guess I need to find someone eilling to prescrive and iversee it. Fiest stop will be the oncoligist so we shall see.

    We are past the chemo stage and its just steroids snd palluative oversight so there is nothing to loose.

    For anyone interested here are some relevant articals:

    Cancer-fighting combination targets glioblastoma

    Date:May 30, 2019Source:Boston CollegeSummary:An international team of researchers combined a calorie-restricted diet high in fat and low in carbohydrates with a tumor-inhibiting antibiotic and found the combination destroys cancer stem cells and mesenchymal cells, the two major cells found in glioblastoma, a fast-moving brain cancer that resists traditional treatment protocols.

    www.sciencedaily.com/.../190530154220.htm

    We're not “DON” yet: optimal dosing and prodrug delivery of 6-Diazo-5-oxo-L-norleucine

    Kathryn M Lemberg, James J Vornov, Rana Rais, Barbara S Slusher

    Molecular cancer therapeutics 17 (9), 1824-1832, 2018

    scholar.google.co.uk/scholar

    Bioanalysis of 6-diazo-5-oxo-l-norleucine in plasma and brain by ultra-performance liquid chromatography mass spectrometry

    Jesse Alt, Michelle C Potter, Camilo Rojas, Barbara S Slusher

    Analytical biochemistry 474, 28-34, 2015

    scholar.google.co.uk/scholar


    Reviving lonidamine and 6-diazo-5-oxo-L-norleucine to be used in combination for metabolic cancer therapy

    Diana Cervantes-Madrid, Yair Romero, Alfonso Dueñas-González

    BioMed research international 2015, 2015

    scholar.google.co.uk/scholar

  • Hello 

    Here in the UK it's unlikely you will find an oncologist who will prescribe or be willing to do this on the NHS. 

    If you go private you may come across a hopeful doctor willing to help. We are at same stage with my son and he's just on palliative care now so would be interested to see how you get on. 

    Madesp