Panitumumab and folfiri

Hi Lini

I am going to tag in Star74 to see if they had panitumumab.

I have read that the dermatologist can get involved if it’s bad . I would certainly ask what the side effect management is and when /how to access it .

Take care and hope treatment is successful.

Court 

Hi Lini

I was on cetuximab and folfiri which is very similar.  I actually found the regime very manageable.  As you are probably aware, it affects the outside of the body which made a welcome change to be honest!  The side effects are different for everyone however, I think it’s pretty common to get some kind of skin rash whether it be spots, dry skin patches, itchy skin but it is cumulative and I didn’t need to seek treatment for mine until a good few cycles in.  I was given antibiotics to take daily and the dose could be increased if I had an outbreak.  Out of all the lotions I tried, I found Dermol 500 to be the best which was provided by the hospital, it can be used as a soap and as a moisturiser.  I had mine in the summer so I had to be very careful in the sun, I couldn’t even stand in front of a window with the sun coming through as it felt a bit like sunburn.  
After 12 cycles, my neck did get very sore and red and I was put on a break but I know people who have had over 100 cycles and they tolerate it very well.  Just be sure to let the team know of any reaction, use shower gel for sensitive skin, moisturise and keep out of the sun.  As court says, the dermatologist can assist if necessary.

Good luck with it all, oh and by the way, it done a fantastic job of shrinking the little blighters!

Michelle. X

@Star44 many thanks for your reply it's just scary going into the unknown. He sailed through his first lot of chemo which was folfox and pocxy ocxy  managed half way before stopping ocxy due to nerve damage. This is a different regime I just wanted people who have had this thier stories I know everyone reacts differently. Can I ask how long have you been doing it  xx

I know, it's the unknown, but at least he kind of knows what to expect with the infusions, even though it was a long time ago. I found this easier than poxy oxy, I didn't even notice it for the first few, just a bit of flaky skin on my face.  I was on folforinox from Dec 21 then cetuximab was added and oxy was dropped. Stayed on folfiri with cetux until Aug when I had a break for surgery.  I had scans after every 4 cycles and it was def cetux that caused the most shrinkage.  He can do this, they have so much available now to deal with any side effects.   Wish him all the best, and you of course.xx