Any Ideas Please?

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My husband has stage 4 bowel cancer, extended right hemi undertaken in 2020, but aprox 6/9 months later spread to retroperitoneal, both lungs and and 

left supraclavicular.

He has been on Longsurf and Bevacizumab for almost a year now.

The problem is he having an awful lot of problems every time he eats, excruciating pain in his stomach the last 3 months. Even though he is on a 6 week break the problem has continued.

Any idea what this can be please? There is no bloating. The consultant said in November this was unusual and he was prescribed codeine.

Many thanks in advance.