Do chemo side effects get worse each cycle? Folfox

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My husband is having Folfox and had bad side effects after 1st chemo cycle. He had vomiting, nausea, diarrhoea, dizziness, tiredness, migraine but worst of all he couldn’t get his words out, was very confused, disoriented and behaving very strangely. He was also weak.

His next cycle is next week and I’m worried he will have even worse side effects.

Is the first treatment the worst or does it get worse each treatment?

  • My side effects got worse with each round. But given the effects you are describing I would discuss with his team about next steps. The level of mental confusion seems above and beyond anything I have heard of