Colon cancer with liver and adrenal metastases

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Hello there,

My mother was diagnosed with colon cancer in 2014, made the surgery and everything was alright. Unfortunately she didn't checked her out regullary and we discovered in the late 2021 that she have 1 liver metastase and 2 adrenal metastases (one in the left and one in the right one), but no relapse in colon.

We started all the treatment process, made 5 sessions of neoadjuvant chemoterapy in order to shrink the tumors with FOLFIRI + cetuximab which turned out to be the right treatment untill now because in 3 months all the tumors have shrunk by half due to the late MRI that we've had and now we're suitable for surgery. For example, in january the liver metastase had 44/46/45 mm and now the same tumor have 25/30/25 mm. 

Now we should made the resection. We're from Romania but for this case we want to go in Turkey because of they're experience in this kind of cases as we heard. The main question for us right now is what is the best approach. If is the conventional surgery of resection, ablation, cyberknife or any other method? 

Thank you for your time and I'm sorry for my bad english,

Have a nice day!

  • Morning  welcome to the forum !

    Firstly your English is excellent! Sorry to hear about your mum . I don’t know much about the adrenaline gland . However my mum has had two liver resections . She went for the surgical option both times for clinical reasons . The location of her mets plus the volume of her spread meant that was the best approach for her to capture the microdisease disease .

    Her last surgery for her liver was back in 2010 and her liver has remained clear and functions well . The other aspect you might want to consider is her age and overall health . My mum was 69 at the time , in good overall health and due to the size of the resection was at the upper age bracket for this extent of surgery here in the U.K. . 

    Others have used Radio frequency ablation here for solitary tumours . I will tag in  . This is also a very good approach and my mum’s oncologist said they are giving surgeons a good run for their money .

    I wish her every success with her treatment .

    Take care ,

    Court 

    Helpline Number 0808 808 0000

  • Thank you , always a relief talking with you.

    If somebody experienced any of the methods listed above, or has been treated for adrenal glands please share your story here, it will help.

  • Apologies  I have just realised we have chatted before !

    I will tag in  she has used Radio Frequency Ablation to treat lung mets . Although I different location it’s the same technique so her experience might give you some insight particularly around planning your stay .

    Take care ,

    court 

    Helpline Number 0808 808 0000

  • Hello, I doubt I can be of much help to you here - but @court has factored me in - simply because I had Lung Ablations on two small tumours in my Lung in Oct. '20. which were successful at that time.However, it was dependant on how large, how deep, & position of tumours.

    I have no idea/ experience of Ablations in any other area - so, I can't comment here. All I can say is that the Lung Ablation procedure I experienced was very non invasive surgery. I had GA & was out the next day - & was able to resume normal life immediately. No pain, just two plasters on the tiny insert wounds.

    Wishing your mother all the best with your decisions,

    Marianne x

  • Hi Stug132. Sorry it has taken so long. I had radiofrequancy ablation on a liver met last April. I went in stayed overnight, they put you into a ct scanner but you are under GA, so you don’t know what is going on. They use a needle, this I think as prongs at the end and it opens on impact with the  liver met and blasts it. I went home the next day without any side effects although it says you can get flu like symptoms. It was quick and painless. Hope all your treatment goes to plan. Sending hugs xx

  • Thank you for telling me this, hope you're good right now and cured :D All the best too

  • No problem! I'll have my mother liver and adrenal ablation too in April this year. They say that they can't do the adrenal ablation on the both adrenals due to the high risk of adrenal insufficiency, but we'll have a second ablation 3-4 weeks after the first one so  we hope that is the best choice for us.

    It is very helpfull to me and my mother your response and also 's because you confirmed us the lack of pain. My main question about ablation remains and I hope you people can answer me. This ablation procedure burns the entire tumor? I mean there is any risk that will remain some tumorous cells around or something like that or usually after ablation the tumor is gone in this place forever.

    Thank you both for your answers and also  for tagging you for this one.

    <3

  • That was exactly my thought, when I was given the all clear after the procedure. I thought that the tumour would be blasted into masses of tiny cells that would seed elsewhere. Apparently, that's not the case....they are simply burned with radio frequency - & become scar tissue.

    It is not always 100% successful - sometimes the procedure just shrinks the tumour, though does tend to stabilise them - so that they are often not a danger.

    However, because of the non surgical ease of this treatment - it can be performed many times.

    I felt very fortunate to have undergone this.( In the UK, it is not carried out in every hospital) My procedure was Oct. '20. I had a CT two months ago - showing I am still all clear.

    Many best wishes

    Marianne