Urothelial

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Hi everyone.
My husband was diagnosed with urothelial bladder cancer a year ago. He is on immunotherapy ( pembrolizumab and enfortumab). He is also on steroids because the immunotherapy has destroyed the part of his pituitary gland that controls cortisol. He has awful blisters all over his feet that have been continuously appearing for a few weeks. 
Has anyone else experienced this and have any tips on how to deal with them? 
It makes walking any distance impossible as his feet are so sore. 
His oncology team have said it’s a common side effect & to apply steroid cream & moisturiser which he does religiously, but it is making no difference. 
Thanks

  • Hi DamnC,

    Sorry to hear about your father's feet. I had peripheral neuropathy after a different type of immunotherapy which is like pins and needles they say though I felt it as more a stabbing pain.. That made walking very unpleasant and was a real nuisance as I walk a lot as exercise and to run errands.

    I found a podiatrist who made me some comfortable orthotics (insoles)  that have helped a lot. I had some others before but we found that my feet had changed over time and these orthotics are specifically made to enable my feet to spread out as well as cushioning them better. I now wear them every day and have regained my love of walking. 

    Steroid cream (which I use for eczema) comes in different levels. Maybe they need to prescribe a stronger version. I was given steroid tablets to combat my neuropathy - and they stopped the immunotherapy. I had already had my bladder removed as well as Gem/Cis chemo so my immunotherapy treatment was more of a belt and braces thing. 

    I moisturize my feet with CCS foot cream (from Boots). That seems quite effective to me. I have to be careful not to use perfumed creams because of allergies.  Maybe that would help your father? Either way a good podiatrist may have seen such a reaction before so would be helpful. 

    I pay or my foot care but maybe in your area there are NHS podiatrists or the hospital treating him could refer him. Sore feet are no joke.

    All the best,

    Latestart

  • Thank you for your reply. 
    Glad to hear you found a solution for your feet, it’s so debilitating when you can’t get around properly.  
    Unfortunately, my husband can’t even put shoes on at the moment as the blisters are all over the top of his feet, toes and ankles. Any kind of pressure is painful. 
    We will bring it up again at his next appointment and see if they can recommend anything else