do you have to be in total remission for allo STC

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hi there, my husband has Non-Hodgkins Lymphoma in his bone marrow - diagnosed in May last year and had 6 rounds of R-Bendamustine, which didn't work and then just finished 6 rounds of R-Chop, which also didn't work. So disappointing! So, the auto STC scheduled for August has been cancelled and our consultant has talked about a donor transplant - they have already tissue typed him to see if they can find a match.

My question is, will they go ahead with the allo transplant if he can't get into remission? How does this work? I think he has to have some more intensive chemo, but as his disease has so far proved resistant, I'm worried that it will prove resistant to the next lot of treatment too - and then the transplant can't go ahead.

Does anyone have any knowledge about this. I know our consultant will talk to us about this when we have more of a plan, but just wondering what other's experiences have been.

Thanks!

  • Yes, he is currently have a break from chemo as he has had two regimens in quick succession and they are now trying a targeted drug for him. the salvage chemo will be the next option if this one doesn't work.

  • , it can be so complicated.

    There was no way to get my rare type of Non Hodgkin’s Lymphoma into remission.

    I had had multiple relapses over the 14 years leading up to it becoming aggressive so there was no other option other than roll the dice, go for my two Allo’s and let my body fight with my brothers Stem Cells.

    My body killed the first set of Stem Cells within 6 months but the second set of Stem Cells eventually took control and I eventually achieved full metabolic remission in Sep 2016 for the first time in over 17 years ((hugs))

    Mike (Thehighlander)

    It always seems impossible until its done - Nelson Mandela

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