Sleepless night

Hope you managed some shut eye last night.Did not want to disturb you if you had gone to sleep,that's why late reply at the moment trying to keep my eyes open as I have a busy day tomorrow with hospital appointment.

Anabell

Hi my friend, I hope you don't mind but I read your profile on the glioblastoma forum, and I'm truly sorry for everything your wonderful family has to contend with, having our diagnosis is as nothing compared to seeing our loved ones having a difficult time, but in the last year my eldest daughter and our kids mum, have both defied a prognosis of 1 year, to be recently told their both cancer free,  if this had happened just 3 years ago, the outcome would likely have been very different, so there's always a little hope to cling onto, my final treatment is failing, but my family is well, I'm happy.

Eddie 

Hi Eddie I’m so sorry to hear your treatment is failing and your family have had a hard time, but it’s nice to hear they are all well. My middle son worked for cancer research Uk at a university not on the research side but he had to go to a lot of lectures and visit cancer wards and he said they have come on leaps and bounds since then. All my family have had bad hearts so I was a bit shocked in a way when they said cancer as it dose not run in the family.I looked at maggiies but unfortunately there is not one near me. I don’t mind you looking at my profile

Anabell

Sorry I seem to have replied to a message sent to somebody else that’s what tiredness dose for you

Thank you Anabell, I appreciate that my friend, CRUK are amazing, as are all those who work for them, I'm sure your very proud of your son, of all of them.

I was in healthcare for 15 years, mostly in cancer and palliative care, retiring just 5 years ago, and as you said, therapies and drug treatments have moved on enormously, with improvements in existing treatments and new ones coming up all the time.

My mum's lung cancer, was, until mine the only cancer in our side of the family, but our kids mum's family weren't so lucky, almost every female in her family had ovarian cancer, none survived till Lesley, so knowing the girls, should they get it will have, with regular testing, a very good chance of cure which is such a comfort.

I too have a bad heart, from birth, which by some miracle is still working, Amongst other things I have an aortic valve defect, an enlarged aorta 54mm-how it hasn't popped I've no idea, I have 3 kinds of Angina, ACHD and have had 7 stents in the last year, so there's always hope my friend.

I'm sorry you don't have a Maggies near you, but the relaxation course they do, which helped me so much, is available online, be positive my friend.

Eddie xx 

I hope your appointment was a positive one mate, I have my fingers crossed for you.

Yeah, I am the same mate, I would happily end it all tomorrow if it meant my family could be healthy. It is fantastic that they making huge progress with some cancers and amazing that both your daughter and kids mum are now cancer free. Hopefully there will be a breakthrough for glioblastoma at some point, the standard drug temozolomide has been around since 1999 I think. Gutted for you mate that your treatment is now starting fail, take care and apologies for initially missing your reply.

No apology necessary my friend, and  I'm with you regarding family. and being hopeful; and with the big breakthroughs with genetics allowing for personalised treatments and huge improvements in immunotherapies and targeted therapies and the use of AI, I've not given up hope, my cancer has never responded to immunotherapy, but after some research, emails and phone calls, I found my local Uni has developed a drug which is amazing at exposing prostate cancer cells to the immune system. they need to edit a virus to carry this drug to the cells safely, which they are in the process of doing, a little hope my friend.

Eddie