Capox - cold socks and mittens for the oxaliplatin infusion

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I start adjuvant capox next Wednesday after pan proctocolectomy with permanent iliostomy on 1st July. Just 2 positive lymph nodes so next step adjuvant capox for 3 cycles.

I had my new patient talk with the chemo nurse today and asked if I could try the oxaliplatin infusion hand and foot icing to try and lower risk of peripheral neuropathy. The hospital don’t offer this protocol.

The data I have seen looks good with statistical significance even in smaller studies. Looks like only a few hospitals in the UK have the electrical kit but I would be happy to buy the mitts and socks which use the gel packs. Logistical nightmare as we live an hour from the hospital and would need plenty of spare frozen gels to maintain low temps for the 2+ hours of infusion infusion. The hospital can’t offer any help with fridge or freezer space and really don’t support this protocol.

Looks like my stoma may misbehave during chemo so keeping my hands working and useful is really important to me. I have bought diclofenac and udderly smooth moisturiser to help with the capecitabine risk of palmar / plantar skin problems and would like to try icing if it might help lower the risk of oxaliplatin CIPN.

And advice please? 

  • I am Sharon, one of the nurses on the Macmillan Cancer Support Line.

    It is positive that you are trying to prepare as best you can for treatment and it is understandable that you want to avoid side effects as much as possible.

    As you have found in your research, there is evidence that limb cooling can reduce the risk of peripheral neuropathy, although it can’t stop it completely.

    Hand and feet cooling is not yet offered routinely. If you were to provide the mitts yourself, that may still pose a problem for some local hospitals, as it is not only the absence of equipment that is the problem, it is also the extra time needed to support this (and freezer space, as you have found already).

    If your local hospital doesn’t have the equipment or the capacity to support your request, they should be able to refer you to a different hospital who can. Larger cancer centres may be more likely to support hand/foot cooling, as they have more of a focus on research and new technology. The major cancer centres in the UK are the Royal Marsden, the Christie, Barts, Cambridge University Hospital, University College Hospital and the Royal Surrey. Clatterbridge have been trialling cold hand and feet mitts since 2023.

    Your consultant should be able to tell you which hospitals near you have the capacity to offer (or support) limb cooling. If not, there may be local options in the private sector (your consultant would still have to do a referral for you). There is likely to be a cost implication, but at least you would be reassured that it was being carried out at the correct temperature and with the correct standards in place.

    We are here for you if you need a chat. As well as our support line, we have webchat, and a bowel cancer forum on our online community, where you can get support from people who are in a similar situation.

     

    Sharon

    Clinical Information Nurse Specialist

    Ref; SA/AMc