Hormone therapy for metastasized endometrial cancer now in lung.

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I've been offered hormone therapy before immunotherapy. I tried HRT some years ago to try to help menopause symptoms. I was on this for approximately 6 months with no significant improvement. Is it worth trying?

  • Good morning Gran W,

    Thank you for getting in touch and welcome to our online community, I hope you find it supportive. My name is Helen and I am one of the Cancer Information Nurse Specialists on the Macmillan Support Line.

    I’m sorry to read your endometrial cancer has now spread to your lungs. I hope you are coping and have support around you. I can see you have joined the womb and lung cancer forums, so I hope you find them supportive and informative too.

    I understand your thinking around the HRT you had in the past and whether the hormone therapy for your endometrial cancer is worth trying.

    When hormone therapy is recommended for your type of cancer, this treatment uses hormones or hormone-blocking drugs to treat cancer. It’s not the same as the hormone therapy given to ease the symptoms of menopause.

    Hormone therapy can be used in this way to treat advanced endometrial cancer or cancer that has come back after treatment.

    Treatment options are recommended depending on what type of treatment you’ve already had. As your cancer team have decided you’re suitable for hormone therapy and immunotherapy, you may be offered the following options:

    • Hormone treatments include medroxyprogesterone or megestrol acetate, letrozole, arimidex, fulvestrant
    • targeted treatments and immunotherapies include pembrolizumab, lenvatinib and dostarlimab

    You may have questions to ask your consultant and clinical nurse specialist about your individual treatment options. If you have any queries about how the hormone therapy works and potential side effects, you can get back in touch with them so you fully understand how these treatments work before you start them.

    You are also very welcome to get in touch with us to talk things through. Sometimes a two-way conversation can be helpful so we can fully understand your current circumstances. It also gives you the opportunity to ask us questions and we can offer other avenues of support which may be beneficial for you.

    I hope this information is helpful but if you have any more questions please don’t hesitate to get back in touch.

    Best wishes,

     

    Helen, Cancer Information Nurse Specialist 

     

    You can also speak with the Macmillan Support Line team of experts. Phone free on 0808 808 0000 (7 days a week, 8am-8pm) or email us. 

    Ref/HeP/LJ