I have having the worst hot flushes at the moment. I have been in Tamoxifen for 2 and a half years but the hot flushes are getting worse. I am not sleeping and hardly functioning during the day. I have 3 fans on me constantly. I have tried all the self help remedies but nothing helps. Is there any medication I can take with Tamoxifen that helps. I have heard about Venlafaxine. Is this possible? Thanks, Aarah