Pathology query and adjuvant chemo for non mucinous adenocarcinoma grade 3 ?

  • 1 reply
  • 42 subscribers
  • 130 views

My 76 yr old Mum has had an upper right lobectomy for NSCLC. There were 2 nodules and the pathology was Non Mucinous adenocarcinoma grade 3, lymphovascular invasion, pleural invasion.  PT2a, NO, Pl1, RO and the the second nodule was in situ with no lymphovascualr or pleural invasion. 

She had a suspected PE and a CT PA was performed which noted some changes in her other lung that werent there in Feb this year.

The surgical team have discharged her from them and back to to referring lung physician. There is no further treatment planned other than surveillance scanning.

My understanding is that grade 3 is poorly differentiated, fast growing and aggressive, and this is evidenced by invasion into lymphovascular system and pleural lining; thus making metastasis or recurrence highly likely? Therefore I would have expected adjuvant chemo or radiation or possibly immunotherapy  ( although I dont have details of the molecular testing).

Please could you clarify my understanding and would you expect further treatment in this situ? We have no referral to an oncologist, just a FU appt with LUNG CNS mid July. 

Thanks

  • Dear Sar0178

    Thank you for getting in touch. My name is Fiona and I’m one of the Cancer Information Nurse Specialists here on the Macmillan Support Line. I see that you’re also a member of the lung cancer forum, I hope that you’re finding it to be a supportive space for you.

    I’m sorry to hear about your mum, this must be a worrying time for you and it’s normal to have questions.

    Firstly, we have no access to NHS records so we are unable to comment on specific treatment decisions, however we can give you general guidance.

    Whilst the ‘RO’ in the pathology report suggests that all of the tumour was removed during surgery it is understandable that you have questions given the tumour type and grading.

    It would be worth contacting your Mum’s Clinical Nurse Specialist (with your Mum’s consent) and ask her to explain the treatment decision in more detail. This would have been agreed at their Multidisciplinary Team meeting after a consideration of all the information they have available about her.

    If, following this, you still have concerns your Mum can request a second opinion which can be done through either your Mum’s GP or hospital team.

    Supporting someone you love with cancer can be very difficult so please do take time to look after yourself. You are always welcome to give one of the nurses a call. Talking things through may feel better for you and we’re always happy to help.

    I hope this information helps to guide you.

    Best wishes,

    Fiona S

    Cancer Information Nurse Specialist

    Ref: FS/SM-G