Question re nodule in left lung after immunotherapy

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Hi I was diagnosed with Stage 4 metastatic melanoma in 2022 I had 13 sessions of immunotherapy ( invo) ending in October 2023 previous scans showed a small nodule on left lung had decreased in size. The melanomas both primary and secondary have been on my left hand side first one about 16 years ago had lymph nodes removed 2 out of 3 had cancer cells.

recent scan in Feb got results yesterday show increase in nodule size on left lung very slight nodule was 4 mm now 5 mm they did have MDT discussion just going to keep eye on me with further tests and scans 2 months. I received info by call it was early and I did not ask further questions I was concerned by MDT meeting was I wrong to be. I have side effects from treatment include accelerated arthritis all joints so mobility reduced otherwise fairly healthy Indo have recurring dry cough I told Oncologist about accept I am probably overthinking it.

  • Hi Basil,

    Thanks for getting in touch. My name is Sarah and I’m one of the cancer information nurse specialists.

    I’m sorry to read about your ongoing symptoms following the immunotherapy. I wonder if the drug you mentioned in your post was Nivolumab. One of the common side effects are muscle and joint pain which could be a contributing factor to the arthritis. I hope you are getting support with the reduced mobility from your GP or a rheumatologist.

    Lung nodules are quite common when people are having scans for an unrelated reason. They may not have caused any symptoms but in this situation it is known as an ‘incidental finding’.

    Having concerns about a slight increase in size is understandable, however it is reassuring that following the Multidisciplinary Team Meeting they don’t feel it’s necessary to carry out any further tests at the moment, such as a biopsy. This is likely to be because the area is so small there would be risks involved.  The right thing to do would be to keep a close eye on it and repeat the scan so they can compare it to the last one for any changes.

    If this is something that will continue to worry you, it would be a good idea to get in touch with your nurse specialist at the hospital, so that they can give you reassurance that this is something they are actively monitoring. It’s also important to let them know if you feel the dry cough you have already mentioned to your oncologist gets any worse.

    I really hope this information was helpful.  Please know, you can always give us a call to talk things through further.

    Take care and best wishes,

    Sarah (Cancer Information Nurse Specialist)

    You can also speak with the Macmillan Support Line team of experts. Phone free on 0808 808 0000 (7 days a week, 8am-8pm) or send us an email or use webchat.

    Ref: HW