My husband had 5 cycles of Chemo and Immunotherapy. His Cancer markers were downtrending but recent CT shows progression of disease in liver and abdomen. He suggested FOLFOX as 2nd regimen. Seems like a logical step based on our research. He DOES have the IDH1 mutation, and we heard of a pill (Tibsovo) that the CCF said could be taken in conjunction with this chemo treatment. Does anyone have any advice on this? Concerns? Our oncologist said he wasn't too familiar with treating at the same time, but we have read and heard from the foundation members that this is common. How do we "push" to see if this is something that could be done simultaneously? We are running out of time and I would hate for this to be my husband's 3rd option, if it could help prolong his life asap. Of course, we have to see how my husband responds to the FOLFOX. The oncologist was optimistic that my husband would respond positively. We don't want false hope, but we still believe in hope. Can anyone help us ?