CA125 Ovarian Cancer

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Are there any studies detailing a correlation between CA125 level and mortality/morbidity? Thank you

  • Hello JAHC87,

    Thank you for writing in your question to us at ask a nurse. My name is Carla, and I am one of the Cancer Information Nurses that work on the Macmillan Support Line.

    The CA125 blood test checks for raised levels of a protein called CA125. It helps diagnose or monitor ovarian, fallopian tube or primary peritoneal cancer.

    It can also be raised due to non- cancerous conditions and other types of cancers.

    It is only one part of diagnostics, and is not always raised when cancer is in early stages.

    There aren’t studies that directly link CA125 to mortality or morbidity as it is not always an accurate marker of disease.

    You may want to have a look at NHS NIHR, it will have a searchable database for ongoing studies. Or you may wish to discuss with your healthcare team.

    You might also find it helpful to speak to one of our nurses on the support line. We are open 7 days a week 8am-8pm. You can call us free on 0808 808 0000 or contact us via webchat from our website.


    Best wishes


    Carla, Cancer Information Nurse Specialist  


    You can also speak with the Macmillan Support Line team of experts. Phone free on 0808 808 0000 (7 days a week, 8am-8pm) or send us an email.