Fentanyl

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I have just discovered this post. My husband has advanced bowel cancer and has currently been prescribed fentanyl patches, He gets these patches changed on a weekly basis. He is currently in hospital just now recovering from a sepsis infection. His palliative nurse noticed that when she saw him on the ward that he did not have his patch on from last week and thinks it may have come while going through A & E and moving around different wards. She said they were going to administer the fentanyl through a drip or pump as they were giving him anti-sickness meds intravenously also and he is also still receiving antibiotics. I was unable to get up to the hospital today and phoned him instead and he sounded really tired and groggy. I believe the Fentanyl can cause the person to feel really tired and sleepy and he was able to tell me he slept most of the day away. Is it possible this has been due to getting the Fentanyl intravenously or could it be a combination of that the antibiotics and anti-sickness meds. Thanks.

  • Hi Patty K,

    My name is Helen and I’m one of the Nurses with the Macmillan Support Line. Welcome to our online community. I see you have joined several of our groups, I hope you are finding them supportive.

    I’m sorry to hear that your husband is in hospital and that he is experiencing unpleasant symptoms.

    Nausea, vomiting and drowsiness are all common side effects of Fentanyl and antibiotics can also make people feel sick.

    Fatigue is also a common symptom of many different infections. It is a normal part of the body’s response to fighting an infection. Usually, the fatigue goes away quickly once the body has dealt with the infection. 

    So, it could be the Fentanyl or antibiotics causing his symptoms or, as you suggested, a combination of all three.

    Hopefully his symptoms will improve as he recovers from the infection, stops the antibiotics, and can go back onto a Fentanyl patch.

    I’m glad to hear that your husband has a palliative nurse involved in his care. It would be helpful to speak to her about your husband’s symptoms so she can explain what they are planning to do to get on top of them.

    I hope this information helps. Please feel free to get back in touch if you want more information or support.

    Best wishes,

    Helen K,

    Cancer Information Nurse Specialist 

    You can also speak with the Macmillan Support Line team of experts. Phone free on 0808 808 0000 (7 days a week, 8am-8pm) or send us an email

    Ref/CF