Genetic test understanding

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Hello,

I'm 31, I was diagnosed with HG DCIS 8cm lump in my right breast. I've had the mastectomy + implant reconstruction and now waiting for my results.

Now during this time I had a genetics test which I've not discussed with the consultant yet fully as she will do that on the 17th November but they have advised me it's negative.

My problem is that my family is cursed with cancer.

My grandfather died of lung cancer (I understand with his cancer, smoked from 11 all his life, so i expected this outcome) my great aunt with breast cancer, my mother breast cancer twice, my aunt breast cancer, my sister ovarian cancer and now DCIS (result frome core biopsy) with myself.

If this doesn't scream genetic i don't know what does. My husband is cross with me as I wasnt happy with the results. Its not that I'm not happy it's that I can't comprehend the results.

It's clearly runs in the family but the mutation gene isn't there. So why has it hit almost every single female in my family on my mother's side. Also I'm 31, I was always told I would get breast cancer by my mum when she got it, I just thought I would be in my late 40s early 50s.

I just fully expect to have that mutation gene. Is it wrong to not believe it. Is my husband right to be cross with me for this.

Can I get some help in understanding please

Tricia T- Macmillan over 2 years ago

Hi Mocana18

Thanks for getting in touch with us. My name is Tricia and I’m one of the Cancer Information Nurses on the Macmillan Support Line.

I am sorry to hear about your recent diagnosis but hope that you are recovering well from your surgery.

Waiting for results can be a worrying time. It is good that you have been told your genetic test is negative. I would imagine they have carried out BRCA1 and BRCA2 testing.

It sounds like the results of the negative result has left you with mixed emotions and some doubt which can be confusing for both yourself and your husband. Cancer treatment itself can affect your emotions. You need reassurance and clarification and a chance to get your questions regarding the genetic results answered at the appointment on the 17^th November. It will be a good idea to have your questions written down in advance to help you to focus at the appointment

Most cancers develop because of a combination of chance, getting older and our environment rather than because we have an inherited cancer gene fault. Unfortunately there is now a 1 in 2 chance of developing cancer in our lifetime .

However, it’s understandable that you are concerned regarding the amount of family members who have had cancer. The main inherited genes and cancer types include the BRCA gene faults. Family history can be assessed by looking at the ages at diagnosis, types of cancer and the relationship to yourself. It is probably worth having as much information regarding the family history ready to discuss with your Consultant.

You may wish to discuss having a referral to a genetic counsellor regarding this history. A referral can be made by the Consultant or your GP.

As we are not directly involved with your care and unable to access NHS records, we are not able to comment on your specific circumstances, but I hope this is helpful.

Please don’t hesitate to get back in touch at any time.

Sending best wishes,

Tricia
Macmillan Cancer Information Nurse Specialist

You can also speak with the Macmillan Support Line team of experts. Phone free on 0808 808 0000 (7 days a week, 8am-8pm) or send us an email.

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Genetic test understanding