Hi
I was diagnosed with ER8 HER2 negative invasive ductal breast cancer with low volume bone metastases in June 2022.
I am currently on Zoladex injections every 3 months (from 22nd July)
Abemacaclib 150mg bid (from 1st August)
Letrozole 2.5mg sid (from 19th August)
Denosumab sc every 4 weeks (from 23rd Sept)
Accrete 400iu vit d and 600mg Ca sid (from 28 sept).
I also have just one kidney (congenital). My blood results have generally been good with wbcc, neuts, hgb, plt all being normal or low end of the normal range. My crea did elevate to 140 but I was told this can happen with Abemacaclib and doesn't reflect kidney function.
My main issue is an extremely dry mouth/relentless feeling of thirst. This started around 2 days after Denosumab injection (my vit d and calcium levels were normal). And extreme tiredness. I went to my gp who found blood in my urine from a dipstick test but no bacteria was cultured. A few days later I had a blood test as my symptoms worsened, they were OK but I had drank around 9-10 pints of water the day before the blood test.I have tried attaching my results from this test. Last night my mouth was so dry it stopped me sleeping. My night sweats have worsened since the Denosumab too. My tiredness is so extreme that I can sleep 10- 11hours at night and still need a 1-2 hour nap in the morning and afternoon the following day. I can't hold a conversation for more than 10 minutes so it's impossible to communicate with friends and family. My temperature has been normal throughout. The only other sign has been blood tinged shots from my nose which started in September.
I have tried contacting my oncology ward and gp but don't seem to be getting anywhere. What can I do to help my dry mouth. I have tried sips water (now limited to 2-3L a day), boiled sweets and chewing sugar free gum, which only helps slightly.
Any tips or advice would be gratefully received.
Thanks
