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Denosumab

BernIre
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Hi all, I'm a hormone receptor-negative, HER2+ metastatic breast cancer patient receiving Paclitaxel, Pertuzumab and Trastuzumab on the first week of each cycle, Paclitaxel on the second week and then a third week off. I have osteoporosis that predates this relapse and take a Prolia (Denosumab) 60mg injection every six months to protect my bones. This is my first injection while on chemotherapy and I'm wondering if it's safe? My doctor said it was fine, but didn't really stop to think about it and I'd value a second opinion if anyone has had any experience!

  • Hi Bernie,

    Thanks for getting in touch.

    I’m Kirsty one of the cancer information nurse specialists on the Macmillan support line.

    It is only natural to feel anxious before starting a new cancer treatment. I can understand why you are concerned about the effect this may have on a pre-existing condition, and the Denosumab you currently take.

    Before prescribing any cancer treatment, your consultant will have looked through your current medication, to ensure it was safe to prescribe. If they had any concerns, they would consult the hospital pharmacist, prior to prescribing.

    Why not give your cancer nurse specialist (CNS) or your consultant a call for some added reassurance? It is important that you go forward into treatment trusting the decisions your cancer team make and feeling safe.

    Best wishes

    Kirsty, Cancer Information Nurse Specialist 

     

    You can also speak with the Macmillan Support Line team of experts. Phone free on 0808 808 0000 (7 days a week, 8am-8pm) or send us an email. 

    Ref/HK

     

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