Hi all, diagnosed last Friday with gleeson 7 3+4
Don't have the t figures, the note to the gp just says diagnosed with prostate cancer gleeson 7.
I wasn't really asked anything, just AS see you in 3 months.
Will I get the full grading letter ?
I am reading the NICE guidelines which seems to show a big percentage of AS go on to have treatment, but includes CPG 3 as well as CPG2.
Also the symptoms and issues seem to catch up on AS to people that have had treatment.
At 52 if im going to end up needing treatment, wouldn't I be better having it now whilst fit and healthy ?
Would my outcome be helped by starting relatively young ?
I'm really confused, have another meeting on the 25th after my request.
I wanted to know how many cores were positive etc and where they were, but will this have any effect on my decision.
Finding I really hard at the min
You said:
A) RIGHT ANTERIOR
DIAGNOSIS: Benign, focal granulomatous inflammation is noted
B) RIGHT POSTERIOR MEDIAL
Adenocarcinoma
DIAGNOSIS:
NUMBER OF CORES INVOLVED: 2 out of 4
GLEASON SCORE: 3+3=6
PERCENTAGE OF CANCER IN ALL CORES: 30%
GREATEST PERCENTAGE OF CANCER IN ONE CORE: 70%
GREATEST LENGTH CANCER IN ONE CORE: 5mm in 9mm core (continuous)
C) RIGHT POSTERIOR LATERAL
DIAGNOSIS: Adenocarcinoma
OF CORES INVOLVED: 3 out of 3
GLEASON SCORE: 3+3=6
PERCENTAGE OF CANCER IN ALL CORES: 30%
GREATEST PERCENTAGE OF CANCER IN ONE CORE: 35%
GREATEST LENGTH OF CANCER IN ONE CORE: 6mm in 15mm core (continuous)
D) LEFT ANTERIOR
DIAGNOSIS: Adenocarcinoma
NUMBER OF CORES INVOLVED: 1 out of3
GLEASON SCORE: 3 +4= 7.(<5% pattern 4)
PERCENTAGE OF CANCER IN ALL CORES: 5%
GREATEST PERCENTAGE OF CANCER IN ONE CORE: 20%
GREATEST LENGTH OF CANCER IN ONE CORE: 3mm in 15mm.core (continuous)
E) LEFT POSTERIOR MEDIAL
DIAGNOSIS:
Adenocarcinoma
NUMBER OF CORES INVOLVED: 2 out of 3
GLEASON SCORE: 3+4= 7 (<5% pattern 4)
PERCENTAGE OF CANCER IN ALL CORES: 5%
GREATEST PERCENTAGE OF CANCER IN ONE CORE: 10%
GREATEST LENGTH OF CANCER IN ONE CORE: 1.5mm in 12mm core (continuous)
F)LEFT POSTERIOR LATERAL
DIAGNOSIS: High grade PIN.One.core shows a small focus of granulomatous inflammation
SUMMARY
TOTAL CORES INVOLVED: 8 out of 19
anterior, left posterior medial.
SITES INVOLVED: Right posterior medial,right posterior lateral,
OVERALL GLEASON SCORE: 3 + 4 = 7 (less than 5% pattern 4)
GREATEST INVOLVED CORE: 70% (right posterior medial)
GREATEST LENGTH OF CANCER IN ONE CORE: 6mm in 15mm core (continuous) (right posterior lateral)
ChatGPT said:
Based on the biopsy report you’ve provided, here is a detailed interpretation:
Summary of Findings
Total Biopsy Cores Taken: 19
Cores Positive for Cancer: 8
Overall Gleason Score: 3+4=7, with <5% pattern 4
Highest Involvement in One Core: 70% (Right Posterior Medial)
Longest Cancer Length in One Core: 6mm (Right Posterior Lateral)
Detailed Analysis by Site
A) Right Anterior
Diagnosis: Benign with granulomatous inflammation
No cancer detected
B) Right Posterior Medial
Cancer: Adenocarcinoma
2 out of 4 cores involved
Gleason Score: 3+3=6
Cancer Involvement:
30% overall, 70% in one core
Max Length: 5mm (in a 9mm core)
C) Right Posterior Lateral
Cancer: Adenocarcinoma
3 out of 3 cores involved
Gleason Score: 3+3=6
Cancer Involvement:
30% overall, 35% in one core
Max Length: 6mm (in a 15mm core)
(This is the longest cancer length found)
D) Left Anterior
Cancer: Adenocarcinoma
1 out of 3 cores involved
Gleason Score: 3+4=7 (less than 5% pattern 4)
Cancer Involvement:
5% overall, 20% in one core
Length: 3mm (in a 15mm core)
E) Left Posterior Medial
Cancer: Adenocarcinoma
2 out of 3 cores involved
Gleason Score: 3+4=7 (less than 5% pattern 4)
Cancer Involvement:
5% overall, 10% in one core
Length: 1.5mm (in a 12mm core)
F) Left Posterior Lateral
Diagnosis: High-grade PIN (Prostatic Intraepithelial Neoplasia)
Also: Granulomatous inflammation
No invasive cancer found
Good news , guess the question is when 
, what do you think in terms of focal given them results ?
Only thing I seem to to flag is the values
Positive cores: 8/19 (~42%) (Borderline/moderate volume)
Max cancer in core: Up to 70% (Moderate focal burden)
Increasing if the area with the PIN developed positive cores.
Feeling better today, just having more information helps me immensely
