FOLFIRINOX and Cetuximab side effects

FormerMember
FormerMember
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Good morning, this is my first post.

I was diagnosed with stage 4 bowel cancer that has spread to my liver. The main tumour is a near blockage of the descending colon, but I haven't required a stoma. I then have a number of small tumours on my liver.

I have had two chemo cycles. The first was just FOLFOX, and although a lot of nausea and sickness it was tolerable. Two weeks later for cycle two my oncologist added in oxoliplatin and Cetuximab. The side effects this time have been near unbearable. Does anyone else have experience with this and can reassure me it will get better or suggest ways to cope?

The days of treatment and wearing the pump were OK ish, but for the 8 days since I have been getting turned inside out. Really bad stomach cramps and constant loud gurgling. Everything that comes out is liquid and quite explosive and the loperamide do nothing. I'm sick a lot and can't keep any food or liquid down. I am so weak and losing more weight. I'm under 40 years old and have gone from competing at sport at a national level to not being able to get up the stairs in 4 months! I am motivated to get through this, it's not lack of trying to get food or drink in me, or keep it in. It just doesn't work. Is this all normal, does it get better? Does the body learn to cope??

Thank you!

  • So good to hear . What a relief for you . It’s not till you see what someone goes through that you realise how dehydrated impacts the body .

    But you are in a much better place and hopefully the reduced dose will bring the required balance . My mum only had a 10% reduction but such a difference it made 

    All the very best for your next cycle and for a brilliant Christmas.

    Court 

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