My dad has recently been diagnosed with Cns lymphoma, large aggressive diffuse B cell. He was admitted to hospital on the 3rd June following a seizure, he has had various tests and scans to reveal a mass on his brain. Over the last month before his diagnosis his speech was becoming more blurred and he struggled to get the words out. His movement has become shuffly too. He has recieved his first dose of methotrexate chemotherapy last Friday and since then he is very confused, restless, and is being quite aggressive. Are these symptoms side effects of the drug? He has not slept for 3 days? He is still in hospital as the doctors won't send him home while he is so restless and confused. I really do feel that if he came home he would be a bit more settled? I would be very grateful for some advice. Thank you