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Hi ,I'm a little confused .I saw my consultant 2 weeks ago I had had BCR-ABL test I was told if it came back negative I would have ET .I received a letter with my diagnosis jak2 negative myeloproliferative disorder .Are they the same as it doesn't explain ? Thank you Debs
Hi Debs (wickedwitch),
Thanks for getting in touch and welcome to our Online Community.
My name is Ellen and I’m one of the nurses working on the Online Community answering questions. I hope you don’t mind but I’ve moved your question to Caroline, who is one of our professional volunteers. She is a Macmillan Nurse who works and specialises in looking after people with Leukaemia and Myelodysplasia and Myeloproliferative disease and would be best placed to answer.
She will aim to get back to you in 2 working days.
Best wishes and take care.
Ellen-Macmillan Online Digital Nurse Specialist.
Thanks for your question. The short answer is yes! Essential Thrombocythaemia (ET) is in a class of diseases called Myeloproliferative neoplasms. Your consultant would have checked your BCR -ABL to rule out CML (chronic myeloid leukaemia). He/ she also would have checked for JAK-2.
JAK 2 (Janus kinase 2 ) is a protein which regulates blood cell production and can be mutated in ET. The mutation is an acquired mutation and affects approx. 50% of ET patients.
This link will take you to MPN Voice which is based at Guys & St Thomas'. They are a national charity providing information, patient support and patient information days locally. They have loads of information and advice for sufferers of ET.
I hope this helps, if you have any other questions, please come back to me
Caroline - Macmillan Information Nurse Specialist
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