Although we make every effort to ensure accuracy, Macmillan Cancer Support cannot accept liability for this information, or for third-party information such as other websites to which we link. If you are concerned about your health you should consult your doctor. Please bear in mind that your question can be read by others - don't post your contact details or any other information that could personally identify you. All answers will be based on information that is correct at the time of posting.
Hi, I'm taking tamoxifen following a mastectomy. The side effects are similar to those of the menopause. I understand that natural progesterone cream can help with the symptoms of menopause. Is it appropriate for me to use natural progesterone cream alongside tamoxifen to help with these side effects? I am 56 and was having regular periods prior to starting on hormone treatment although I would have expected to begin menopause at any time due to my age. I have no idea what my progesterone levels are.
Thanks for getting in touch. It’s common to have lots of questions when you are trying to manage treatment side-effects.
When you are diagnosed with hormone positive breast cancer, your results will show the presence of oestrogen and progesterone hormone receptors on the cells. As these can encourage cancer cells to grow then the tamoxifen is used to slow down and stop their growth.
Some women are positive for progesterone and others are negative, but these women are all offered hormone treatment. It may be helpful to have a chat with your breast care nurse or hospital team.
Whilst looking on some of the American forums we can see women use progesterone cream however it is not common practice to do this in the UK.
There are different ways of trying to manage menopausal symptoms that involve non-hormone drugs or complimentary therapies. The breast cancer group can offer lots of practical tips and advice from others.
If you want to speak to one of the nurses then just give us a call on the Macmillan Support Line.
Best wishes and take care
Lorraine-Macmillan Information Nurse Specialist
Safe payments by:
We're here to provide physical, financial and emotional support. So whatever cancer throws your way, we're right there with you.
© Macmillan Cancer Support
© Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man
(604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company
number 2400969. Isle of Man company number 4694F. Registered office: 89 Albert Embankment, London SE1 7UQ. VAT no: