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Endo Predict Test

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I had the OncoType DX Test which came back with a low score, so no Chemo was recommended. Surgeon ordered Endo Predict Test that has come back in high risk and Chemo recommended with a 6% benefit at 10 years, or risk of distant recurrence 15%.  My Team don't want me to have Chemo, they believe it would be detrimental to stop the Hormone Treatment and go to Chemo now as I've been on the Letrozole for almost 6 months. I had Grade 2 and 2x micromets. Could you please advise.

Ellen M-Macmillan
Posted by

Hi peterawake,

Thanks for getting back in touch with us.

I’ve had a look at your profile and can see that you’ve had a tough time since your diagnosis, and that you’re also having to cope with your husband’s worsening Parkinson’s. You’re right to say that you feel that you’ve both been through more than enough.

I can also see that you’ve joined our supportive breast cancer group and that you’re actively supporting others despite what you’re going through. It never fails to amaze me the amount of support that you all give each other here on our Online Community.

It can be confusing when you have had a second opinion and they don’t agree with your team. This can make it harder to know what to do for the best, or to feel confident about what your team are saying to you.

It’s difficult for us as nurses to give you advice about what treatment you should have. Decisions about this are made by a group of doctors (MDT). However, chemotherapy is often recommended to start as soon as possible after surgery rather than 6 months later. This is known as adjuvant treatment to decrease the chances of your cancer coming back. The benefits of having chemotherapy is better when it is given earlier.

Studies have only reported the potential benefits of chemotherapy and then giving hormonal therapy. And the results from the EndoPredict Test would have reported the potential benefits based on treatment given this way.

I know that you’ve already sought a second opinion, but this was in relation to having chemotherapy after your surgery. It might be worthwhile asking to be referred to another team to ask if they would consider giving you chemotherapy despite having hormonal therapy for 6 months.

Often it can be helpful to call our Support Line on 0808-808-0000 and talk to one of our nurses about how this is affecting you. If you think that would help we are open every day 8am till 8pm.

Best wishes and take care.

Ellen-Macmillan Online Digital Nurse Specialist.